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side effects associated with these medications include dry mouth, dry eyes, and constipation (Sarma 2012). One concern with these medications is that they can cause increased urinary retention, although studies in men with good emptying (post-voiding residual urine volume less than 250 mL) have not identified any adverse effects associated with urinary retention. Surgery, bPH can also be treated surgically. The purpose of surgery is to either remove the prostate or reduce its size, thereby relieving the lower urinary tract symptoms. In addition, some men experience breast enlargement and tenderness. Gutschein für April 2019 besorgst und beim Shop an der Kasse anwendest.
They may also increase levels of nitric oxide, a compound that relaxes smooth muscles in the lower urinary tract. Many antimuscarinic drugs have been approved to treat symptoms of overactive bladder, including darifenacin (Enablex tolterodine (eg, Detrol fesoterodine (Toviaz trospium chloride (Sanctura oxybutynin (Ditropan and solifenacin (Vesicare) (Sarma 2012). One BPH treatment option includes 1-adrenergic receptor blocker medications, since the 1A subtype of these receptors is thought to be the main regulator of smooth muscle tone in the neck of the bladder and prostate (Nickel 2008a).
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This is significant because dutasteride inhibits both type 1 and 2 isoforms, whereas finasteride inhibits only type. One postulated mechanism is that phosphodiesterase-5 inhibitors block a signaling pathway that causes smooth muscle contraction. Medications in the 5-reductase inhibitor class block the conversion of testosterone to dihydrotestosterone, helping to shrink the prostate and prevent further growth. Activation of muscarininc receptors stimulates contraction of the detrusor muscle. Beim beliebten Versandhändler kannst du eine Vielzahl von bekannten Marken und Kategorien durchstöbern, auf welche du deinen Life Extension. Antimuscarinics, many men with BPH also have an overactive bladder, which can cause symptoms such as urinary urgency and incontinence (Elterman 2012). These medications may work via several mechanisms. This procedure can also cause transurethral prostatectomy syndrome, a serious complication in which fluid used to irrigate the surgical area enters the intravascular space. Some important considerations should be taken into account when choosing between finasteride and dutasteride in the management of BPH. Other complications include voiding failure, urinary tract infections, and bleeding during or after surgery (Reich 2008). This muscle contracts and squeezes the bladder to facilitate urination, and remains relaxed otherwise, allowing the bladder to stretch and fill.
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